The FT-IR spectra of PCL/nHA scaffolds in accordance with nHA concentration were shown in Fig. 2(a). In the spectrum of nHA, the characteristics of the phosphate group (P O) appeared at the wavelengths of 961 and 1087 cm −1.Spectrum peaks corresponding to nHA were more clearly observed as the concentration of nHA …
There is a significant decrease in the water contact angle of PCL-PLA polymer (from 125.5° to 98°) by adding nHA. PCL-PLA/nHA/Zeolite scaffold has a contact angle between PCL-PLA/Zeolite and PCL-PLA/nHA. Generally, PCL presence in nanofibers structure has decreased the hydrophilicity of scaffolds. Download : Download high-res …
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Although PCL/nHA nanocomposites enhance cell proliferation and osteoconduction in vitro, a homogeneous dispersion of a high concentration nHA (up to 60% (wt/wt), resembling the natural bone composition) ... This may occur through topography-induced modulation of cell mechanotransduction .
The resultant PCL/nHA composites were cut into small pieces for future use. 2.2. Melt electrohydrodynamic of microscale PCL/nHA composite scaffolds. The schematic process to fabricate PCL/nHA composite scaffolds is illustrated in Fig. 1 b. Briefly, PCL/nHA composite pieces were loaded into a stainless syringe that was immersed in a ...
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Near-field direct-writing melt electrospinning (NFDWME) technology has attracted great attention because of its many advantages, such as its environment-friendly process, high speed, and shape controllability [1,2,3,4,5].By introducing the high-voltage electrostatic field into precise 3D equipment, NFDWME is able to prepare an …
In the current study, designed polycaprolactone (PCL) scaffolds enriched with nano-hydroxyapatite (nHA) were fabricated through three-dimensional (3D) . Subsequently, human mesenchymal stem cells (hMSCs) were seeded onto PCL-nHA scaffolds for osteogenic differentiation to establish the pre-metastatic niched …
It was concluded that the more appropriate process parameters for preparing PCL/nHA scaffolds were a spinning voltage of -4 kV, receiving distance of 4 …
Figures 1(e), 1(f), 1(g), and 1(h) show that the longer the porous scaffold supports remained in PBS, the more significant the thickening on the walls of the PCL and PCL/nHA 10 wt% pores was. For the rest of the scaffolds, which have a higher percentage of nanoparticles, the fibrous appearance may be appreciated when the pores are stretched.
The PCL/nHA scaffold prepared from NaCl/PEG 4000 (20/50) presented more macropores (>50 μm) with interconnectivity and showed higher strength and improved bioactivity than …
PCL was melted in a beaker at 120 °C. nHA powder was added to the molten PCL and stirred to obtain a homogenous mixture. The material was left to cool before being cut into small pieces and stored at room temperature. Similar techniques have previously been reported in the literature for preparation of PCL/nHA composite materials …
In the current study, designed polycaprolactone (PCL) scaffolds enriched with nano-hydroxyapatite (nHA) were fabricated through three-dimensional (3D) . …